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7 Due to its longer half-life, semaglutide has prolonged CNS effects, regulating appetite and metabolic processes

No contraindications to GI side effects: Patient can manage or tolerate nausea during the titration period

Frequency of Injections During the Initiation Phase During the initiation phase, semaglutide injections are typically administered once a week, on the same day each week

Exposure to canonical ferroptosis inducers, including erastin, RSL3, and glutamate, triggers a rapid loss of mitochondrial membrane potential (m), thereby impairing oxidative phosphorylation and compromising respiratory ATP production [101, 102]

Expiry Date: September 2027