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17,22, This provides a rationale for using GLP-1 together with GIP agonism, as GLP-1 may lower glucose sufficiently to unmask the incretin effect of GIP, while GLP-1 action may overcome the potentiating effect of GIP on GCG secretion
Metformin is a lower-cost option compared to GLP-1 medications, suitable for those seeking modest weight loss or who dont qualify for or prefer to avoid GLP-1 drugs and needles
They slow gastric emptying, so food stays in the stomach longer, and help decrease hunger signals to the brain, making it easier to follow a balanced eating plan
[5] While GLP-1 receptor agonists should not be prescribed solely for cholesterol lowering, certain patient populations may derive particular benefit from their lipid and broader cardiometabolic effects
Granata, A
