In a 2025 review, Sikiric and his team report that the study found the peptide was safe and well-tolerated, but they have not published the data
Supports immune response, detoxification, and skin health
Antioxidants are crucial in neutralizing oxidative stress, and preliminary research suggests that this compound may play a role in mitigating cellular damage caused by free radicals
So, if you're feeling unwell due to a deficiency, restoring B12 levels might help you feel well enough to eat normally, but it's not "making" you gain weight in an unhealthy way
Common concerns include: Feeling tired more often than usual Low energy levels Tingling or numbness sensations Difficulty concentrating Weakness These symptoms can have many causes, so speaking with a healthcare provider is the best way to understand your individual situation
Stopping & maintenance What is known about stopping retatrutide without tapering