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Consultado el 25 de enero de 2026

Exenatide, and in particular its extended-release (ER) formulation, is the GLP-1 receptor agonist with the broadest clinical evidence, including motor and cognitive improvements in an open-label phase 2 study [161] which persisted 12 months after drug withdrawal [162], as well as motor improvement in a placebo-controlled phase 2 trial [163]

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Subgroup analyses by drug type, duration of treatment, and patient characteristics similarly showed no concerning signals