10.1042/BST20200270 Summary Keywords GLP-1, immunemetabolic signaling, metabolic disease, neuroendocrine peptides, orphan receptors, peptide therapeutics, polypharmacology Citation Niazi SK (2026) Beyond GLP-1: underexplored peptidereceptor systems as the next frontier in drug discovery
Benefits and risks of bariatric surgery in adults: a review
The public conversation around Gwyneth Paltrow, Andrew Huberman, GLP-1s, and peptides has made more people aware of this emerging medication
As estrogen levels fall, muscle and liver cells respond less efficiently to insulin
Adding it to the mix might create yet another additive or synergistic benefit
The glucagon receptor response and the thermogenic effects it produces may be less susceptible to the receptor desensitization that affects GLP-1 pathways