Purity: Independently tested (COA available)
Still, side effects from B12 supplements are possible, especially at higher doses, and include: Headache Nausea Vomiting Fatigue Weakness Diarrhea Tingling in the hands and feet Nasal spray Vitamin B12 is also available in a nasal spray
Ribbon diagram of Drosophila melanogaster dmGSTD1 (PDB: 3MAK)
One of the RCTs found significant mean improvements in Clinical Global Impressions-Improvement (CGI-I) score and cellular methylation capacity, but not in the Aberrant Behaviour Checklist (ABC), Social Responsiveness Scale (SRS) or GSH metabolism, with those who had the lowest methionine status at baseline (suggesting impaired methylation capacity) significantly more likely to respond to supplementation
If subcutaneous injection is completely off the table for you, oral products become the obvious choice by default
Trends Mol Med (2019) 25(2):11223