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These alterations, secondary to heat damage, lead to increased concentrations of endotoxin and reactive oxygen species (ROS) [52], promoting significant damage to the intestinal mucosa by disrupting cellular membranes and the tight junctions [42]

Systemic Cost Considerations Beyond Raw Material Price In addition to effective delivery costs, using SAG also brings many other hidden cost savings

In such cases, the long plasma half-life of administered IgG-based therapeutics is a clear disadvantage, and thus the ability to quickly remove them from circulation may save lives

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