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A case of SUDEP in a patient with Dravet syndrome with SCN1A mutation

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Proceedings of the National Academy of Sciences 1987

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FIGURE 4 Changes in Aging and Disease States As elegantly documented by Dean Jones over many years ( Regulation of Hepatic Redox State Reactive oxygen species also increases in response to excess fuels, as described in section Redox Components in perfused liver: lactate plus pyruvate and FFA stimulate ROS production

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Epigenetics 4 , 399403 (2009)

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a Patients who attended the final scheduled visit b Patients who completed treatment with assigned treatment according to the end-of-trial form Note: Rescue medication = use of new anti-diabetic medication as add-on to treatment and used for more than 21 days with the initiation at or after randomization and before last day on treatment Source: Clinical Study Report

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