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Insulin resistance is a key factor in MASLD pathogenesis it drives increased release of free fatty acids into the liver and promotes hepatic de novo lipogenesis, essentially telling the liver to manufacture more fat than it can export or burn

PMID: 10604470 Bowers CY

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A review of progress on targeting LDL receptor-dependent and -independent pathways for the treatment of hypercholesterolemia, a major risk factor of ASCVD

It is commonly listed as Bitter Orange Extract and is known as the active compound in Citrus Aurantium

Designed to support the same appetite-regulating hormone pathway targeted by injectable weight loss drugs, without the need for a prescription or needle