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Topical cosmetic formulations are sold separately as ready-to-use serums and creams
Wegovy (semaglutide), Zepbound (tirzepatide), and Saxenda (liraglutide) are all FDA-approved for weight loss in people with obesity or overweight who have a weight-related health condition like high blood pressure, type 2 diabetes, or obstructive sleep apnea
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88,89 Sirtuins, a family of nicotinamide adenine dinucleotide (NAD)+-dependent enzymes, regulate cellular metabolism, mitochondrial function, and stress responses
OTC products may contain ingredients that support weight loss through different pathways, but they do not activate the GLP-1 receptor itself
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