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Selected publications: Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ FEBS Letters, 1988

A cytokine storm produces inflammation in an inflammatory response to harmful substances, bacteria, viruses, and more

Feinberg C, Housley NA, Bhatt DL, et al

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Two enzymes are involved in glutathione synthesis

in fibroblast culture models it stimulates collagen, elastin, and glycosaminoglycan synthesis at picomolar to nanomolar concentrations (10 to 10 M), and modulates metalloproteinase (MMP-1, MMP-2, MMP-9) activity and their inhibitors (TIMP-1, TIMP-2), functioning as a general regulator of extracellular matrix remodeling ( Mechanistic research establishes that GHK activates TGF- and integrin 1 pathways during tissue repair, attracts immune and endothelial cells to wound sites, and restores gene expression patterns toward a healthier fibroblast phenotype in models of aging and radiation damage ( A 2018 review in IJMS characterizes its role in collagen production, nerve outgrowth stimulation, and dermal stem cell marker expression ( For Research Use Only