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While mean values for all semen parameters at all time-points remained within the normal ranges and did not meet predefined criteria for a clinically significant change (30%), 2 subjects in the dutasteride group had decreases in sperm count of greater than 90% from baseline at 52 weeks, with partial recovery at the 24-week follow-up

doi: 10.1111/jcmm.16205 57 WildRARizzoMCliftonSCarminaE

Higher levels of nitrites among other biomarkers such as short-chain fatty acids, lipopolysaccharides, beta-cresol, and bacterial toxins in children with ASD supports the theory that ASD is a braingutmicrobiome disorder [39,40]

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