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Topical limitations: Limited penetration beyond superficial skin layers

Inflammation, oxidation, together with the imbalance of MMPs/TIMPs, has been reported widely to involve in the pathogenesis process associated with COPD

The tips of DNA strands are covered with Telomeres (4), a repetitive sequence of nucleotide bases whose critical function is to protect the DNA and prevent any loss of genetic information while a cell undergoes cell division

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Avoid applying strong acids or strong retinoids at the same time on very sensitive skin