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The protein expression and activation of FAK and paxillin were determined by Western blot analysis, and the phosphorylation levels of both FAK and paxillin were dose-dependently increased by BPC-157, while the total amounts of protein were unaltered

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mTOR is involved in cell proliferation and apoptosis, autophagy, and arthritis by involving various signaling pathways

I would also be cautious with berberine in anyone taking medications for diabetes, blood pressure, blood thinning, or immunosuppression, because berberine may interact with several medications and could increase the risk of side effects or low blood sugar depending on the situation. People with chronic medical conditions, liver or kidney concerns, or anyone taking multiple medications should speak with their medical provider before using berberine, says Katz

Focusing on a balanced diet (like fruits, vegetables, whole grains and lean proteins) is another option