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For a 250 g/ml solution and a research subject weighing 70kg, targeting a 10 g/kg dose: 10 g/kg 70kg = 700 g total dose 700 g 250 g/ml = 2.8ml injection volume For repeat-dose protocols, researchers often split daily doses into twice-daily administrations (e.g., 5 g/kg every 12 hours rather than 10 g/kg once daily), which maintains more stable plasma concentrations

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28 Sick day management GPs can play an important role in reinforcing the principles of sick day management, especially those related to medication use, in people with DKD

Your provider may recommend dietary changes or dose adjustments instead, which are typically more effective long-term

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