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Its primary function

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Increasing systemic levels of L-Arginine has been demonstrated to significantly improve endothelial function in individuals with essential hypertension, compromised flow-mediated dilation, arterial stiffness, chronic heart failure, impaired glucose tolerance, and type 2 diabetes-all of which are common concomitant medical conditions associated with Erectile Dysfunction (ED).

In the body, it is 90% protein-bound

L., & Holton, K

a 2025 literature-and-patent review in Pharmaceuticals summarizes its multifunctional, mostly-preclinical profile (PMC11859134)