Possible Side Effects and Contraindications B12 injections are generally safe, even in high doses
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For years, oral supplements represented the standard approach to addressing B12 insufficiency
For malabsorption (e.g., pernicious anemia), injections are often preferred, though some clinicians still use very high-dose oral regimens (NIH ODS)
Reasons are stated below: Does not accumulate in body: Vitamin B12 Injection For Dogs Is Water Soluble-Picture Courtesy: ThinWorks Vitamin b12 injection for dogs does not accumulate in body because it is water soluble
The physician should provide information to the patient about the signs and symptoms of hepatotoxiciy that should cause alarm (e.g., nausea, fatigue, lethargy, pruritus, jaundice, right upper quadrant tenderness and "flu-like" symptoms)