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Figure 1 illustrates the age and sex distribution of the patients with reported psychiatric adverse events

This has led to increasing scientific interest in incretin hormones and incretin interactions, and several compounds based on dual- and multi-agonists are now being investigated for the treatment of metabolic diseases

In chronic kidney disease, loss of kidney epithelial cells leads to glomerulosclerosis and tubular atrophy, whereas interstitial inflammation and fibrosis result from an excess of leukocytes and myofibroblasts

It achieves this by regulating blood sugar levels and improving insulin sensitivity, which reduces the amount of sugar in the bloodstream