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2.2 Study population The study population consisted of patients with overweight or obesity who were prescribed either tirzepatide or other anti-obesity medications, including bupropion, naltrexone, orlistat, topiramate, phentermine, or setmelanotide

Once you figure out what is causing them, you can try to address the issue

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Higher plasma lipopolysaccharide concentrations are associated with less favorable phenotype in overweight/obese men

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This means at least 30 minutes before a meal or 2 hours after