Clinical takeaway: Before initiating semaglutide (subcutaneous or oral), especially in patients with known diabetic retinopathy, an eye examination and careful glycemic monitoring are essential
5 Health Canada's non-fatal MI indication for Wegovy is based on results of the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity (SELECT) trial
This manifests as heavier periods, longer periods, breakthrough bleeding between cycles, or shorter intervals between periods
Their use is associated with better glycemic control and a low risk of hypoglycaemic events in patients for whom other oral antidiabetic drugs (OADs), such as metformin, are not sufficient to achieve adequate glycemic control [1]
The study also found that GLP-1R expression was similar in the retinas of both diabetic and non-diabetic individuals, though GLP-1 levels, associated with neuroprotective ability, were significantly lower in diabetics
Jackson, MD Custom-formulated peptide and IV wellness stacks Safe, evidence-based therapies for real emotional and cognitive support Available as standalone or add-on therapy Ready to Calm the Mind and Unlock Clarity
