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Br J Ind Med 39:355360

Metabolic parameters, tissue inflammation, fibrosis, and macrophage activation were assessed using histology, flow cytometry, gene expression analyses, and immunoblotting

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The putative mechanisms underlying altered body composition with CLA include reduced lipogenesis and increased lipolysis, increased expression of genes that interfere with the maturation of adipocytes [86], increased fat oxidation via elevated activity of carnitine-palmitoil-transferase-1 (CAT-1), reduced activity of lipoprotein lipase, inhibition of adipocyte differentiation, and increased activation of apoptotic pathways in adipose tissue [21, 87, 88]