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Under normal physiologic conditions, intracellular GSH concentrations of neurons are 250- to 500-fold higher than in the CSF, 17 thus limiting the utility of CSF to serve as a biomarker of cellular GSH status

Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis

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3 In mammalian species, the dimeric cytosolic GSTs are abundantly expressed in many tissues and grouped into seven distinct isoenzyme classes termed alpha, pi, mu, omega, sigma, theta and zeta

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