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By mimicking the effects of natural incretin hormones, Tirzepatide enhances insulin secretion, reduces glucagon levels, and slows gastric emptying, leading to improved glycemic control and reduced appetite

( B ) Glp1r versus Ppia expression levels in whole heart atria (Atr) and whole aorta (Aor) as well as FACS-collected cells that are endothelial cells (CD31 + ), immune cells (CD45 + ), or remaining cell types (CD31 /CD45 ) from either chow-fed WT mice or Ldlr / mice fed HFHC diet for 18 weeks

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