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These cells constitute about 3% of total body mass and consume about 20 g (0.1 mole) of glucose per day, representing about 10% of total body glucose metabolism

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At the microbial level, taxa such as Lactobacillus and Bifidobacterium favour TRP availability for 5-HT synthesis, whereas enrichment of pro-inflammatory Proteobacteria enhances immune-driven IDO activation and KYN production [175], directly linking microbial ecology to mood-relevant neurochemical pathways

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