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Compared to obese wild-type control animals, obese IFN- knockouts exhibit better IS, smaller adipocyte size, and lower cytokine expression [79]

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In recent years, accumulating evidence suggests that oxidative stress, mitochondrial dysfunction, and disturbances in iron homeostasis serve as upstream triggers driving these pathological cascades (Luo et al., 2019

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Most patients experience energy dips for 14 weeks as their body adjusts to reduced food intake and slower digestion

doi: 10.1016/s0891-5849(97)00286-4 239 Santos Duarte LanaJ