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Thus, the evidence is not conclusive and the effect may be only small (Platts-Mills et al., 1995)

That behavior is "particularly troublesome" for acetaminophen, an FDA report said, because the drug's narrow safety margin places "a large fraction of users close to a toxic dose in the ordinary course of use. The FDA sets the maximum recommended daily dose of acetaminophen at 4 grams, or eight extra strength acetaminophen tablets

10.1007/s00253-007-1075-9 Appl

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They can help you determine the right dosage and ensure there are no interactions with your current routine