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This led to a significant reduction in portion sizes, as well as long periods without eating, due to lack of hunger

While orforglipron has passed its Phase 3 hurdles without these specific signals so far, the history of pharmacology teaches us that rare, serious adverse events often lurk in the postmarketing shadows

All types of diabetes are increasing in prevalence

A 2025 review of 12 small trials suggested modest gains in natural conceptionbut not in IVF outcomes

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adolescent migraine prophylaxis trials reported renal calculus (less than 1%), urinary incontinence (2% or more), and urinary tract infection (2% or more)