Key Toxicities to Watch as a clinical pharmacist: Renal: nephrotoxicity, rising creatinine Neuro: tremors,confusion, seizures Metabolic: hypertension, QT prolongation, hyperglycemia Electrolytes: K, Mg Heres how we intervene before toxicity takes over: Slash Tacrolimus doses by ~70% when starting Posaconazole TDM every 23 days (dont wait for trouble) Monitor renal function, BP, electrolytes, glucose closely Anticipate the reverse interaction when Posaconazole is stopped tacrolimus levels crash without timely adjustment Key Insight: Pharmacists arent just dose adjusters. We are the safety net that spots silent drugdrug collisions before they harm patients
Cachexia is a metabolic syndrome associated with muscle and weight loss connected to health issues like cancer, chronic obstructive pulmonary disease (COPD) , and heart failure
Exactly how many remains to be seen
There's also a pill now
Inhibition of necroptosis attenuates kidney inflammation and interstitial fibrosis induced by unilateral ureteral obstruction
Our crew will stick by your side every step of the way making sure things are going smoothly towards hitting those weight loss targets
