However, the most significant difference is between systemic circulation (minutes) and topical application on the skin (hours of local residence time)
10.1097/cm9.0000000000000627 [DOI] [PMC free article] [PubMed] [Google Scholar] Yao J., Zhao L., Zhao Q., Zhao Y., Sun Y., Zhang Y., et al
Clinical Translation: Subsequent studies have confirmed these laboratory findings in human subjects, showing that topical and systemic GHK-Cu increases measurable collagen deposition and improves skin structural integrity over 8-12 weeks of use
After its half life, GHK-Cu is broken down by enzymes into its constituent parts: the amino acids glycine, histidine, and lysine, and the copper ion
Frankincense Essential Oil
However, exclusive use of folic acid in treating vitamin B12 deficient megaloblastic anemia could result in progressive and irreversible neurologic damage