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As these options become more widely available, the need for split dosing injectable medications may diminish

For the six conjugation pathways (glucuronidation, glutathione conjugation, sulfation, acetylation, methylation, and amino acid conjugation) that process metabolites downstream of quinone reductase and epoxide hydrolase, see Phase II Conjugation Reactions

For those patients, I tend to take a laissez-faire attitude toward complementary therapies that are not obviously-dangerous