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Inhibition of GCS It is well known [27, 41] that GSH is a competitive inhibitor against glutamate of GCS, the enzyme that catalyzes the synthesis of glutamyl-cysteine

Cerebral small vessel disease encompasses a heterogeneous group of pathological processes involving small arteries, arterioles, capillaries, and venules within the brain, typically measuring less than 400 micrometers in diameter (Pantoni, 2010)

Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on November 25th, 2025

The modest sample size and short treatment duration limited the study, according to investigators

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