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Using caution, however, is warranted, especially since there is no long-term data for humans

Now many caucasian people do have a red tone in their sunspots (along with brown), and you will see that redness diminish, but not the brown

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Aged mice were intraperitoneally injected with 5 mg/kg FOXO4-DRI or PBS as a control every other day for three administrations, and effects were assessed 30 days post-treatment