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Individuals taking tirzepatide (Mounjaro, Zepbound) may be eligible to donate plasma, but eligibility depends on several factors including the reason for use, overall health status, and individual donation center policies

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Pyridinoline (PYD) collagen crosslinks are formed during the extracellular maturation of fibrillar collagens and released into the bloodstream as mature collagens degrade and are considered bone resorption markers (Kuo & Chen 2017)

The numbers of study subjects were uniformly small: the largest study by Ledda et al