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Consulting a doctor before starting tirzepatide is essential to ensure it is appropriate and used correctly

Current and upcoming pharmacotherapy for non-alcoholic fatty liver disease

35 A relatively small open-label study on eight patients with diabetes mellitus and biopsy-proven NASH found that 28 weeks of exenatide treatment made no significant difference in liver histology, and only three of the eight subjects did meet the primary end point of improved histopathology, with 1 to 2 point fibrosis improvement seen in four subjects and fibrosis worsening by 1 point in one subject and staying the same in three subjects

These signals suggest a complication beyond typical influenza that may require urgent evaluation

The modest increases in response rate observed later in treatment were unexpected and may reflect enhanced task engagement following extended sucrose deprivation during the testing phase, when daily training and sucrose access were paused, rather than drug-induced activation

Int J Mol Sci (2023) 24(8):7082