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Exenatide (Byetta/Bydureon) was the first GLP-1 receptor agonist to reach the market (FDA 2005), derived from the venom peptide exendin-4 found in the Gila monster lizard

D-DW built the model, evaluated the data, and wrote the manuscript

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GLP-1 receptor agonists mimic the action of a hormone glucagon-like peptide 1 that the gut secretes after eating