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Chest Pain: Any pressure, squeezing, or sharp pain in the chest

Less dramatic reductions in HGPRT activity do cause hyperuricemia and gout due to the reduced salvage of hypoxanthine and guanine leading to increased uric acid production

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Semaglutide works by mimicking the natural GLP-1 hormone in the body to reduce appetite, increase feelings of fullness, and improve blood sugar control

Since the primary objective of the trial was to assess cardiovascular safety, this may have led to an imprecise estimation of DR risk

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