Safety Profile and Common Side Effects at the Starting Dose Semaglutide at 0.25 milligrams carries a favorable safety profile, with the most frequent side effects being gastrointestinal in natureincluding nausea, constipation, or mild abdominal discomfort
severe stomach pain or bloating
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GI adverse events were the most common class, consistent with the incretin mechanism, and were predominantly mild to moderate
While GLP-1 medications have been approved as treatments for children with type 2 diabetes since 2019, pediatric prescriptions spiked after Wegovys high-profile FDA approval for adolescents in December 2022, which specified that it can be used for weight loss
The blockbuster medications have been hailed as wonder drugs for their profound effects on diabetes and weight loss, but a growing number of doctors are concerned that the medications are triggering or worsening eating disorders in some people