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Constipation was another commonly noted event, reflecting changes in gut motility that are associated with this class of drugs
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This should be personalized rather than guessed
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As the majority of L-cells are located in the distal ileum and colon, the early phase is likely explained by neural signalling, gut peptides or neurotransmitters
Herbal preparations that affect blood glucose levels, such as ginseng, fenugreek, or bitter melon, may have additive glucose-lowering effects when combined with semaglutide, potentially increasing the risk of hypoglycemia particularly in patients receiving other antidiabetic medications
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