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Copper in excess is genuinely toxic, and in a zebrafish model free copper caused heart toxicity (Hsiao et al., 2020) though in that same study the GHK peptide chelated copper and reduced the harm, so GHK-Cu is not equivalent to free copper
Results from how to reconstitute GHK-Cu Cosmetic depend on your goals and circumstances, but most clients see measurable improvements
Lu H, Zhang H, Jiang Y
PTR 33, 20442055
Monitor for injection site reactions, though these are typically mild and self-limited