elevated heart rate tirzepatide Effects of on circulatory overload and end-organ damage in failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial Cardiovascular outcomes of semaglutide and

10.2337/dc23-S014 13 FDA (2021)

Side Effects Common Gastritis Nausea Abdominal discomfort Dyspepsia Serious Peptic ulcer/ GI bleeding Renal impairment Fluid retention/edema Increased BP Hypersensitivity reactions Bronchospasm in asthmatics 8

A new review led by researchers at the Johns Hopkins Bloomberg School of Public Health suggests the answer is mostly reassuring

The obesity drug pipeline remains robust, with next-generation therapies and novel mechanisms progressing through multiple phases of clinical development

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This is exactly what can lead to Ozempic muscle loss