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However, manufacturers marketing AOD-9604 as a supplement cannot make disease or therapeutic claims (e.g., "for weight loss" or "for treating obesity") without violating FDA regulations

doi: 10.1155/2020/3580719 45 LongYTaoHKarachiAGrippinAJJinLChangYEet al

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Elevated levels of A in both plasma and brain have been observed in aging and AD models, potentially resulting from impaired hepatic clearance mediated by reduced expression of liver LRP-1 receptors regulated by PPAR [45, 46]

doi:10.1016/j.molmet.2020.101102 15