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doi: 10.1111/j.1523-1755.2005.00365.x

[1] FDA, Warning Letters, available at: (last visited: Sep

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In addition, in rat endplate chondrocytes, the intervention of IGF-1 up-regulated the expression of MMP-13 through the ERK pathway, thereby inhibiting the decomposition of cartilage [30]

Choosing optimal injection sites and following proper injection technique can minimize local reactions