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One MRS study(Maier et al., 2022) and a number of plasma-based studies(Alabdali et al., 2014

The WHO estimates that more than 1 billion people worldwide are living with obesity, a condition that significantly increases the risk of cardiovascular disease, type 2 diabetes, cancer, and premature mortality

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Key points This manuscript highlights a newly recognized form of diabetes called SAGE-DM, which develops in older or lean individuals due to age-related changes in hormones, immune function, and fat tissue, rather than obesity