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Patients should also be aware that folate supplementation should not be started before B12 deficiency has been treated, as doing so can precipitate or worsen neurological complications

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Amyloidosis associated with dialysis occurs when blood proteins are deposited on joints and tendons, resulting in discomfort, stiffness, and fluid buildup in the joints

Cyanocobalamin may also be used for improving energy levels, boosting metabolism, and promoting healthy skin, hair, and nails

Some healthcare professionals may recommend the combination because of theoretical considerations