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Future Directions and Research Opportunities Triple Agonism and Beyond The success of dual agonism has stimulated interest in triple agonism approaches that add glucagon receptor activation to GIP and GLP-1 targeting

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Among emerging anti-diabetic candidates, glucagon like peptide-1 (GLP-1) based therapies carry special cardiovascular implications, exerting both direct as well as indirect effects

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After deparaffinization and rehydration, all sections were treated with microwaves in 10 mmol/L citrate buffer (pH 6.0) for 10 min for antigen retrieval

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