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The roles of glutaredoxins ligating Fe-S clusters: Sensing, transfer or repair functions

J BioMed Sci

Despite many advances in the attempt to activate NRF2 through different pharmacological approaches, much remains to be done to fully benefit from the various drug candidates able to modulate the cellular antioxidant response mediated by NRF2

While no standardized screening protocols currently exist, clinicians are encouraged to use the five-item Screen for Disordered Eating or SCOFF questionnaire to assess for eating disorders and to ensure patients receive appropriate, evidence based care

This is why medium-chain triglyceride (MCT) oil is sometimes used therapeutically in fatty acid oxidation disorders it provides a carnitine-independent fuel source

Indeed, LCMS analysis of polar metabolites demonstrated no increase in 2-HG levels (Extended Data Fig