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They identified a 38% increased risk of kidney cancer among GLP-1 users compared to non-users, a finding described as marginally nonsignificant but nonetheless concerning given the widespread use of these drugs

The Hidden Cost: How Much Lean Muscle Mass Is Lost on GLP-1 Medications

Exenatide, dapagliflozin, or Phentermine/Topiramate differentially affect metabolic profiles in polycystic ovary syndrome

Longer term follow-up from the cohorts (and when feasible RCTs) will be important to avoid underestimating the true long-term risks for harm

J., Fernhall, B., Regensteiner, J

Small red bumps or mild irritation at the injection site are common and usually resolve within a few days