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& Bhat, M
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The preliminary cardiovascular safety data for DPP-4 inhibitors are promising, and, if the results of long-term cardiovascular studies demonstrate reductions in hard cardiovascular end points, then this may consolidate the position of the DPP-4 inhibitors as the second-line choice for combination with metformin
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Active medications that affect blood pressure or arousal There is little drug-interaction data
Moreover, in the plasma of germ-free mice, a significant decrease (0.005 nmol/mg vs
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