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It activates three transcription factors (FoxO/DAF-16, Nrf-2/SKN-1, and HSF-1) that operate downstream of the insulin signaling pathway [124]

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Instead, they might deprive the individual of important nutrients, and can even lead to eating disorders, the so-called orthorexia, a kind of obsession with healthy eating that leads to an arbitrary elimination of every food deemed harmful to the diet

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doi: 10.1074/jbc.M703713200 60 BersukerKHendricksJMLiZMagtanongLFordBTangPHet al