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(1) -Cu refers to the chemical addition of copper

Reiffel JA, Camm AJ, Belardinelli L, Zeng D, Karwatowska-Prokopczuk E, Olmsted A, Zareba W, Rosero S, Kowey P, Investigators H (2015) The HARMONY Trial: combined ranolazine and dronedarone in the management of paroxysmal atrial fibrillation: mechanistic and therapeutic synergism

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This treatment approach falls short and modified and/or new strategies must be developed [53,54]